Joy (Elizabeth Banks), a traditional 60’s American housewife, is desperate for a second child. However, the wonderful news of her pregnancy is tainted by the threat it poses to her own life. She has nowhere to turn until she stumbles upon the Janes, an underground group of ordinary women united by Virgina (Sigourney Weaver), who risk everything to provide people like Joy with choices. They save Joy’s life and give her a burning sense of purpose: to help other women take control of their destinies.